[NIFL-HEALTH:3792] RE: primary peritoneal cancer and the tumor ma

From: Janicki, Joanne (Joanne.Janicki@RoswellPark.org)
Date: Tue Oct 08 2002 - 12:16:56 EDT


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From: "Janicki, Joanne" <Joanne.Janicki@RoswellPark.org>
To: Multiple recipients of list <nifl-health@literacy.nifl.gov>
Subject: [NIFL-HEALTH:3792] RE: primary peritoneal cancer and the tumor ma
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I am including text from a National Institute fact sheet on "Tumor Markers"
which includes information about CA-125.  Factors other than cancer can
elevate this marker:

"CA 125 is produced by a variety of cells, but particularly by ovarian
cancer cells. Studies have shown that many women with ovarian cancer have
elevated CA 125 levels. CA 125 is used primarily in the management of
treatment for ovarian cancer. In women with ovarian cancer being treated
with chemotherapy, a falling CA 125 level generally indicates that the
cancer is responding to treatment. Increasing CA 125 levels during or after
treatment, on the other hand, may suggest that the cancer is not responding
to therapy or that some cancer cells remain in the body. Doctors may also
use CA 125 levels to monitor patients for recurrence of ovarian cancer. 

Not all women with elevated CA 125 levels have ovarian cancer. CA 125 levels
may also be elevated by cancers of the uterus, cervix, pancreas, liver,
colon, breast, lung, and digestive tract. Noncancerous conditions that can
cause elevated CA 125 levels include endometriosis, pelvic inflammatory
disease, peritonitis, pancreatitis, liver disease, and any condition that
inflames the pleura (the tissue that surrounds the lungs and lines the chest
cavity). Menstruation and pregnancy can also cause an increase in CA 125. "

  The link below is to the fact sheet in its entirety.  I would not put this
in the "easy to read" class that literacy experts would expect, but  this
will at least give you a framework of information about what it can't and
cannot do.

http://cis.nci.nih.gov/fact/5_18.htm


Joanne E. Janicki
Director, Breast Resource Program
Roswell Park Cancer Institute
Elm & Carlton Sts.
Buffalo, NY  14263
716-845-4432
716-845-3098 (fax)



-----Original Message-----
From: Daphen Greenberg [mailto:epedgg@panther.Gsu.EDU]
Sent: Tuesday, October 08, 2002 11:55 AM
To: Multiple recipients of list
Subject: [NIFL-HEALTH:3790] primary peritoneal cancer and the tumor
marker CA-125 blood test


There has been an email floating around about primary peritoneal cancer and
the tumor marker CA-125 blood test. I am hoping that the medical
professionals on this listserv can shed some insight into this, so that we
can know how to direct our learners. According to the email, one out of
every 55 women will get ovarian or primary peritoneal cancer and it is urged
that women ask their doctors to run the CA-125 blood test as part of an
annual physical exam. Apparently, this blood test is inexpensive and simple.
Is there anyone on this listserv who can shed light on this and do you know
of easy to read websites or printed materials that discuss this?

Thanks!



Daphne Greenberg

Georiga State University





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